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1

Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities

Wondrak, Georg T.

Journal:

Antioxidants & Redox Signaling

Year:

2009

Language:

english

File:

PDF, 299.63 MB

english, 2009

2

[IEEE 2015 IEEE International Symposium on Electromagnetic Compatibility - EMC 2015 - Dresden, Germany (2015.8.16-2015.8.22)] 2015 IEEE International Symposium on Electromagnetic Compatibility (EMC) - Increasing electromagnetic compatibility of Contactless Inductive Flow Tomography

Wondrak, Thomas, Ratajczak, Matthias, Gundrum, Thomas, Stefani, Frank, Krauthauser, Hans Georg, Jacobs, Ralf T.

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

3

Skin Stress Response Pathways || Biological Cell Protection by Natural Compounds, a Second Line of Defense Against Solar Radiation

Wondrak, Georg T.

Year:

2016

Language:

english

File:

PDF, 554 KB

english, 2016

4

A Topical Zinc Ionophore Blocks Tumorigenic Progression in UV-exposed SKH-1 High Risk Mouse Skin

Justiniano, Rebecca, Perer, Jessica, Hua, Anh, Fazel, Mohammad, Krajisnik, Andrea, Cabello, Christopher M., Wondrak, Georg T.

Journal:

Photochemistry and Photobiology

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

5

Light from maillard reaction: Photon counting, emission spectrum, photography and visual perception

Georg Wondrak, Thomas Pier, Roland Tressl

Journal:

Year:

1995

Language:

english

File:

PDF, 582 KB

english, 1995

6

The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells

Sarah D. Lamore, Sara Azimian, David Horn, Bobbi L. Anglin, Koji Uchida, Christopher M. Cabello, Georg T. Wondrak

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2010

Language:

english

File:

PDF, 1.95 MB

english, 2010

7

Optimizing the energy status of skin cells during solar radiation

Elaine L Jacobson, Paolo U Giacomoni, Michael J Roberts, Georg T Wondrak, Myron K Jacobson

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2001

Language:

english

File:

PDF, 120 KB

english, 2001

8

Photosensitized Growth Inhibition of Cultured Human Skin Cells: Mechanism and Suppression of Oxidative Stress from Solar Irradiation of Glycated Proteins

Wondrak, Georg T., Roberts, Michael J., Jacobson, Myron K., Jacobson, Elaine L.

Journal:

The Journal of Investigative Dermatology

Year:

2002

Language:

english

File:

PDF, 399 KB

english, 2002

9

Proteins of the Extracellular Matrix Are Sensitizers of Photo-oxidative Stress in Human Skin Cells

Wondrak, Georg T, Roberts, Michael J, Cervantes-Laurean, Daniel, Jacobson, Myron K, Jacobson, Elaine L

Journal:

The Journal of Investigative Dermatology

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

10

Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis

Sarah D. Lamore, Georg T. Wondrak

Journal:

Year:

2011

Language:

english

File:

PDF, 586 KB

english, 2011

11

The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells

Sarah D. Lamore, Christopher M. Cabello, Georg T. Wondrak

Journal:

Cell Stress and Chaperones

Year:

2010

Language:

english

File:

PDF, 664 KB

english, 2010

12

Proteomic Identification of Cathepsin B and Nucleophosmin as Novel UVA-Targets in Human Skin Fibroblasts

Sarah D. Lamore, Shuxi Qiao, David Horn, Georg T. Wondrak

Journal:

Photochemistry and Photobiology

Year:

2010

Language:

english

File:

PDF, 762 KB

english, 2010

13

The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis

Christopher M. Cabello, Sarah D. Lamore, Warner B. Bair III, Shuxi Qiao, Sara Azimian, Jessica L. Lesson, Georg T. Wondrak

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

14

The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A (p21) upregulation in human cancer cell lines

Christopher M. Cabello, Warner B. Bair III, Stephanie Ley, Sarah D. Lamore, Sara Azimian, Georg T. Wondrak

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.32 MB

english, 2009

15

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1

Christopher M. Cabello, Warner B. Bair 3rd, Alexandra S. Bause, Georg T. Wondrak

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 719 KB

english, 2009

16

Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes

Shuxi Qiao, Sarah D. Lamore, Christopher M. Cabello, Jessica L. Lesson, José L. Muñoz-Rodriguez, Georg T. Wondrak

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.86 MB

english, 2012

17

NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis

Georg T. Wondrak

Journal:

Free Radical Biology and Medicine

Year:

2007

Language:

english

File:

PDF, 1.51 MB

english, 2007

18

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

Georg T. Wondrak, Christopher M. Cabello, Nicole F. Villeneuve, Shirley Zhang, Stephanie Ley, Yanjie Li, Zheng Sun, Donna D. Zhang

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

19

The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth

Christopher M. Cabello, Warner B. Bair III, Sarah D. Lamore, Stephanie Ley, Alexandra S. Bause, Sara Azimian, Georg T. Wondrak

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 1.94 MB

english, 2009

20

GLO1 Downregulation in Human Renal Cell Carcinoma Enables Targeted Chemotherapeutic Intervention Using Methylglyoxal as Cytotoxic Heat Shock Inducer

Christopher M Cabello, Shuxi Qiao, Warner B Bair III, Angela L Davis, Jessica L Lesson, Georg T Wondrak

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 399 KB

english, 2010

21

Switching Enemies: The Redox Antimalarial Dihydroartemisinin Targets Human Metastatic Melanoma Cells but not Primary Melanocytes through Induction of NOXA-dependent Apoptosis

Christopher M Cabello, Sarah D Lamore, Warner B Bair III, Angela L Davis, Jessica L Lesson, Georg T Wondrak

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 388 KB

english, 2010

22

Identification of α-dicarbonyl scavengers for cellular protection against carbonyl stress

Georg T. Wondrak, Daniel Cervantes-Laurean, Michael J. Roberts, Jaber G. Qasem, Moonsun Kim, Elaine L. Jacobson, Myron K. Jacobson

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

23

DNA damage by carbonyl stress in human skin cells

Michael J. Roberts, Georg T. Wondrak, Daniel Cervantes Laurean, Myron K. Jacobson, Elaine L. Jacobson

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

24

Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1

Georg T Wondrak, Sridhar Varadarajan, D.Allan Butterfield, Myron K Jacobson

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 345 KB

english, 2000

25

d-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis

Qiao, Shuxi, Cabello, Christopher M., Lamore, Sarah D., Lesson, Jessica L., Wondrak, Georg T.

Journal:

Year:

2012

Language:

english

File:

PDF, 986 KB

english, 2012

26

New Melanoidin-like Maillard Polymers from 2-Deoxypentoses

Tressl, Roland, Wondrak, Georg T., Krüger, Ralph-Peter, Rewicki, Dieter

Journal:

Journal of Agricultural and Food Chemistry

Year:

1998

Language:

english

File:

PDF, 322 KB

english, 1998

27

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

Tao, Shasha, Zheng, Yi, Lau, Alexandria, Jaramillo, Melba C., Chau, Binh T., Lantz, R. Clark, Wong, Pak K., Wondrak, Georg T., Zhang, Donna D.

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

28

DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma

Cabello, Christopher M., Lamore, Sarah D., Bair, Warner B., Davis, Angela L., Azimian, Sara M., Wondrak, Georg T.

Journal:

Free Radical Research

Year:

2011

Language:

english

File:

PDF, 732 KB

english, 2011

29

Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue

Williams, Joshua D., Bermudez, Yira, Park, Sophia L., Stratton, Steven P., Uchida, Koji, Hurst, Craig A., Wondrak, Georg T.

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2014

Language:

english

File:

PDF, 2.15 MB

english, 2014

30

THE MALNOURISHED CHILD: CURE BETTER THAN PREVENTION?

Lamore, Sarah D., Wondrak, Georg T.

Journal:

Year:

1982

Language:

english

File:

PDF, 320 KB

english, 1982

31

UVA causes dual inactivation of cathepsin B and L underlying lysosomal dysfunction in human dermal fibroblasts

Lamore, Sarah D., Wondrak, Georg T.

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

32

The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

Tao, Shasha, Justiniano, Rebecca, Zhang, Donna D., Wondrak, Georg T.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013

33

Redox Chemotherapeutic Intervention Targeting Proliferative Dysregulation in Multiple Myeloma

Qiao, Shuxi, Wondrak, Georg T.

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

34

Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin-induced diabetic atrophy

Whitman, Samantha A, Long, Min, Wondrak, Georg T., Zheng, Hongting, Zhang, Donna D.

Journal:

Experimental Cell Research

Year:

2013

Language:

english

File:

PDF, 2.59 MB

english, 2013

35

Identification of Aurin as an Experimental Chemotherapeutic for the Pharmacological Induction of Proteotoxic Stress Targeting Metastatic Melanoma

Davis, Angela L., Qiao, Shuxi, Cabello, Christopher M., Lesson, Jessica L., Wondrak, Georg T.

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

36

Structure and Potential Crosslinking Reactivity of a New Pentose-Specific Maillard Product

Tressl, Roland, Wondrak, Georg, Kersten, Evelyn, Rewicki, Dieter

Journal:

Journal of Agricultural and Food Chemistry

Year:

1994

Language:

english

File:

PDF, 1.19 MB

english, 1994

37

Maillard Reaction of Free and Nucleic Acid-Bound 2-Deoxy- d -ribose and d -Ribose with ω-Amino Acids

Wondrak, Georg T., Tressl, Roland, Rewicki, Dieter

Journal:

Journal of Agricultural and Food Chemistry

Year:

1997

Language:

english

File:

PDF, 232 KB

english, 1997

38

Pentoses and Hexoses as Sources of New Melanoidin-like Maillard Polymers

Tressl, Roland, Wondrak, Georg T., Garbe, Leif-A., Krüger, Ralph-Peter, Rewicki, Dieter

Journal:

Journal of Agricultural and Food Chemistry

Year:

1998

Language:

english

File:

PDF, 323 KB

english, 1998

39

Photosensitization of DNA damage by glycated proteins

Wondrak, Georg T., Jacobson, Elaine L., Jacobson, Myron K.

Journal:

Photochemical & Photobiological Sciences

Year:

2002

Language:

english

File:

PDF, 336 KB

english, 2002

40

Stress Response Pathways in Cancer ||

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 8.67 MB

english, 2015

41

Stress Response Pathways in Cancer || Targeting Hypoxic Adaptations of Cancer Cells: Molecular Mechanisms and Therapeutic Opportunities

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 370 KB

english, 2015

42

Acute Solar UV Exposure Generates Photodamage-Associated Protein Epitopes in Healthy Human Skin: Implications for Cutaneous Tumorigenesis

Williams, Joshua D, Bermudez, Yira, Lian, Fangru, Uchida, Koji, Park, Sophia L, Wondrak, Georg T

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

43

Redox-Directed Suppression of Malignant Cell Invasion in a Three-Dimensional Skin Reconstruct Model of Metastatic Melanoma

Davis, Angela L., Qiao, Shuxi, Justiniano, Rebecca, de la Vega, Montserrat Rojo, Wondrak, Georg T.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 32 KB

english, 2014

44

The Quinone Methide Aurin Is a Heat Shock Response Inducer That Causes Proteotoxic Stress and Noxa-dependent Apoptosis in Malignant Melanoma Cells

Davis, Angela L., Qiao, Shuxi, Lesson, Jessica L., Rojo de la Vega, Montserrat, Park, Sophia L., Seanez, Carol M., Gokhale, Vijay, Cabello, Christopher M., Wondrak, Georg T.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 6.75 MB

english, 2015

45

The Tryptophan-Derived Endogenous Aryl Hydrocarbon Receptor Ligand 6-Formylindolo[3,2-b]Carbazole Is a Nanomolar UVA Photosensitizer in Epidermal Keratinocytes

Park, Sophia L, Justiniano, Rebecca, Williams, Joshua D, Cabello, Christopher M, Qiao, Shuxi, Wondrak, Georg T

Journal:

The Journal of Investigative Dermatology

Year:

2015

Language:

english

File:

PDF, 1.96 MB

english, 2015

46

The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death

Qiao, Shuxi, Tao, Shasha, Rojo de la Vega, Montserrat, Park, Sophia L, Vonderfecht, Amanda A, Jacobs, Suesan L, Zhang, Donna D, Wondrak, Georg T

Journal:

Year:

2013

Language:

english

File:

PDF, 9.89 MB

english, 2013

47

Stress Response Pathways in Cancer || p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 459 KB

english, 2015

48

Stress Response Pathways in Cancer || Cell Cycle Checkpoint and DNA Damage Response Defects as Anticancer Targets: From Molecular Mechanisms to Therapeutic Opportunities

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

49

Stress Response Pathways in Cancer || Targeting Glycolytic Adaptations of Cancer Cells: From Molecular Mechanisms to Therapeutic Opportunities

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

50

Stress Response Pathways in Cancer || Introduction to Cell Stress Responses in Cancer: The Big Picture

Wondrak, Georg T.

Year:

2015

Language:

english

File:

PDF, 234 KB

english, 2015